Anti Estrogens

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Every athlete knows the effect of aromatization. This is the process of converting substances with high androgenic activity to estrogens. To put it more simply, almost all steroids are based on testosterone derivatives – the male sex hormone. It follows that each of these drugs has a certain degree of androgenic activity.

Anti EstrogensThis entails a sharp increase in the male body of female hormones (estrogens), which leads to unpleasant side effects. The most common among them is gynecomastia. In this case, the male breast begins to develop on a female basis, due to the accumulation of fat in the nipple.

They are easily removed surgically, but there is nothing pleasant for men in this. It is also worth noting that a high content of estrogen in the male body leads to an increased retention of fluid and fat. For bodybuilders, this situation is unacceptable. But a way out of this situation exists – Anti Estrogens drugs. It is about them and will now talk.

The work of antiestrogens

Anti Estrogens drugs
Before proceeding to the description of the drugs themselves and determining the best of them, one should understand the mechanism of their effect on the body. Most often the process of aromatization proceeds as follows. The molecule of the anabolic drug, entering the body, is in a free state and begins to interact with the enzyme molecule – aromatase. As a result of this interaction, the steroid is converted into estrogens.

The thus obtained molecule of estrogen interacts with the receptor of the estrogenic type, thus causing a certain effect. The result of this effect is influenced by the place where the receptor interacting with the molecule of the created estrogen is located. Receptors in the chest cause gynecomastia.

You can avoid this in two ways:

  • Prevent the connection of the steroid and aromatase.
  • Do not allow the created molecule of estrogen to enter into interaction with the receptors.
  • Thus, all antiaromatous drugs can be divided into two groups, depending on their mechanism of action. Those drugs that use the first method are called antiaromatous drugs, and the second group – antagonists of estrogen.

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