Semisynthetic penicillin, is bactericidal, has a broad activity spectrum. Ingibiruet transpeptidazu violates synthesis of peptidoglycan during the period of division and growth, causes lysis of bacteria. Active against gram-positive and gram-negative cocci, some gram-negative bacilli. Effect on Staphylococcus spp. in addition to strains, producyrute penitsillinazou, Streptococcus spp., Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Proteus mirabilis, some strains of Salmonella, Shigella Klebsiella and Haemophilus influenzae. In combination with metronidazole is active against Helicobacter pylori. Β – lactamases destroyed, so the microorganisms-producers of β – lactamase are resistant to the action of amoxicillin.
Amoxicillin Each tablet contains active substance: 250 mg or 500 mg of amoxicillin (in the form of amoxicillin trihydrate) and the excipients: magnesium stearate, talc, brilliant blue Е133, karmuazin Е122, orange yellow E110, titanium dioxide, iron oxide yellow, gelatin. This drug belongs to the group of semisynthetic penicillins, antimicrobial agents, broad-spectrum systemic use. Inhibits the growth of microorganisms that cause infection.
Individual. For oral single dose for adults and children over 10 years (body weight over 40 kg) is 250-500 mg, in severe disease, up to 1 g. For children 5-10 years single dose of 250 mg; age 2 to 5 years – 125 mg; for children under 2 years of daily dose is 20 mg/kg For adults and children interval between doses 8 hours in the treatment of acute uncomplicated gonorrhea – 3 g once (in combination with probenecid). In patients with impaired kidney with QC 10-40 ml/min interval between doses should be increased up to 12 h; when KK less 10 ml/min interval between doses should be 24 hours