The drug has antibacterial properties. Apply with infections of the respiratory and urinary tracts, soft tissues and skin, as well as in systemic infections.
The drug is designed for temporary treatment of bacterial infections caused by sensitive microorganisms:
Use of Augmentin tablets 1 g (875/125 mg) is shown for infection of the female genital organs and gonorrhoea.
The use of Augmentin 1000/200 mg (injectable form) is shown for infection of the female genital organs and gonorrhea, for the prevention of infectious complications in surgical interventions, in most types of surgical interventions on the gastrointestinal tract, pelvic, head and neck, heart, kidney, joint replacement and surgery of the bile ducts.
Infection caused by amoxicillinamoxicillin by microorganisms that are effectively treated by Augmentinom, given the content of amoxicillin. Mixed infection caused by amoxicillineclavulanate microorganisms in combination with augmentinamoxicillin microorganisms — producers of beta-lactamase, may thus be treated by Augmentinom.
Side effects were classified according to organs and systems and the frequency of occurrence. The frequency of occurrence are divided into the following categories: very common (≥1/10), often (≥1/100 and <1/10), infrequently (≥1/1000 and <1/100), rare (≥1/10 000 and <1/1000), very rare (<1/10 000).
Infections and infestations – common: candidiasis of the skin and mucous membranes.
Blood and lymphatic system – rare: reversible leucopenia (including neutropenia) and thrombocytopenia. Very rare: reversible agranulocytosis and haemolytic anaemia, increased bleeding time and prothrombin index.
Immune system – very rare: angioneurotic edema, anaphylaxis, syndrome, similar to serum sickness, allergic vasculitis.
Nervous system uncommon: dizziness, headache. Very rare: reversible hyperactivity and convulsions. Convulsions may occur in patients with impaired renal function or in patients receiving the drug in high doses.
Vascular disorders – rare: thrombophlebitis at the injection of the drug.
Gastrointestinal very common: diarrhoea (when using tablet forms). Often: diarrhea (when using the suspension and injectable forms), nausea, vomiting. Uncommon: indigestion. Nausea often noted in applying the drug in high doses. The above symptoms of the gastrointestinal tract can be reduced by taking the drug at the beginning of the meal. Very rare: antibioticassociated colitis, including pseudomembranous colitis and haemorrhagic (the probability of development is much lower when parenteral administration of the drug), black and hairy tongue.
Hepatobiliary reactions – uncommon: mild increase in liver transaminases were measured in patients receiving beta-lactam antibiotics, but the clinical significance of this is not established. Very rare: hepatitis and cholestatic jaundice. The same effects were noted when using other penicillins or cephalosporins. Hepatitis occurred mainly in males and elderly patients, their occurrence may be associated with prolonged drug treatment. In children, these manifestations had rarely. Signs and symptoms occur during or immediately after treatment, but in some cases can occur several weeks after stopping treatment. These effects are usually reversible. Very rarely (less than 1 message about 4 million appointments) are deaths that always occur in patients with severe underlying disease or the simultaneous administration of drugs that have a negative impact on the liver.
Skin and subcutaneous tissue Uncommon: skin rash, itching and hives.Rare: polymorphic erythema.Very rarely: Stevens — Johnson syndrome, toxic epidermal necrolysis, bullous exfoliative dermatitis and acute generalized absentmindly pustules. In case of appearance of any allergic dermatitis treatment is needed to stop.
Kidney and urinary system – very rare: interstitial nephritis, crystalluria.