Vermodje Exemever, pharmacological action – antitumor, antiestrogenic. Inhibits aromatase (irreversibly binds to the active center of the enzyme and causes its inactivation) and prevents the formation of estrogens. Has an anti-estrogenic effect, while not having progestogen and estrogenic activity, does not affect the synthesis of cortisol and aldosterone in the adrenal glands. If you take the drug in high doses, it shows a slight androgenic activity (due to the 17-hydro-derivative). Increases the level of LH and FSH on the principle of feedback: a decrease in the content of estrogen stimulates the release of gonadotropins in the pituitary gland.
Side effects Exemever can include: fatigue, depression, pain in the head, rash, excessive sweating.The side effects of the drug purely individual. It depends on the sensitivity of the organism to priparaty. Often, the cost of the drug is high enough, but its effective work is not in doubt in its use.
Quantity required exemestane calculated from the use of anabolic steroids, individual sensitivity to inhibitors of aromatase. In the most general case of exemestane dosage equal to 12.5 mg per day. It should be remembered that the use of exemestane is only necessary to control the level of estrogen. Full reduction or removal of estrogen has a negative impact on the body.
The duration of the drug is about 2-4 weeks. When the athlete is not started in time to take aromatase inhibitors and are already visible or pronounced estrogenic side effects should start exemestane 25 mg daily and do not stop taking the drug until the complete disappearance of symptoms of gynecomastia.