In addition, amoxicillin is active against all microorganisms sensitive to penicillin G, for example, streptococci of group A, B, C, G, H, I, M, Streptococcus pneumoniae, staphylococci and Neisseria spp., Not producing penicillinase, Erysipelothrix rhysiopathiae, Corynebacterium , Bacillus anthracis, Actinomycetes, Streptobacilli, Spirillium minus, Pastereulla multocida, Listeria, Spirochaeta (Leptospira, Treponema, Borrelia) and others, as well as various anaerobic microorganisms (including peptococci, peptostreptococcus, clostridia and fusobacteria).
Dosing and Administration:
In acute uncomplicated gonorrhea appoint 3 g once; In the treatment of women, repeated intake of this dose is recommended.
In acute infectious diseases of the gastrointestinal tract (paratyphoid, typhoid ) and biliary tract, with gynecological infectious diseases adults – 1.5-2 g 3 times a day or 1-1.5 g 4 times a day.
In severe infections (meningitis, septicemia), adults – up to 6 g per day in 3-4 doses. Children – 250-500 mg 3 times a day. The duration of treatment depends on the indications and the clinical picture and is usually 5-7 days. With otitis and similar infections in children, two-time administration of Amoxicillin is sufficient. In cases of chronic diseases, recurrent infections, severe infections currents adults appoint 750 mg-1 g three times a day for children up to 60 mg / kg per day divided into 3 doses.
When leptospirosis adults – 0.5-0.75 g 4 times a day for 6-12 days.
When listeriosis adults – 0.5 g 3 times a day for 6-12 days.
Precautions prescribe the drug to pregnant women; Patients prone to allergic reactions. In patients who have increased sensitivity to penicillins, there may be cross-allergic reactions with cephalosporin antibiotics.